Journal article
Automated Insulin Delivery Effects During Driving Among Older Adults with Type 1 Diabetes in a Randomized Trial
S Trawley, HJ Kwon, S Vogrin, PG Colman, S Fourlanos, MH Lee, RJ MacIsaac, DN O’Neal, NA O’Regan, V Sundararajan, GM Ward, SA McAuley
Diabetes Technology and Therapeutics | MARY ANN LIEBERT, INC | Published : 2025
Abstract
Dysglycemia among drivers with type 1 diabetes (T1D) is associated with impaired driving performance, and glucose levels “above 5 to drive” are often recommended for insulin-treated drivers. Evidence for diabetes treatments that support euglycemia while driving is minimal, particularly for older drivers. In this randomized, crossover trial involving adults aged ≥60 years with T1D, we used continuous glucose monitoring (CGM) during driving to compare the first-generation closed-loop automated insulin delivery (AID) versus a sensor-augmented pump therapy. There were 1894 trips undertaken by 8 drivers (median age 68 years [IQR: 64-70]). During AID versus sensor-augmented pump, time in range >5...
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Funding Acknowledgements
The authors would like to thank the study volunteers for their participation. The authors also acknowledge contributions of the clinical trial staff at St Vincent's Hospital Melbourne and The Royal Melbourne Hospital, Melbourne, Australia.